CRS + HIPEC Package

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Surgery Name	Cost	Room	Hospitalization
CRS + HIPEC Package	10999 USD	Private Room + ICU	10-14 Days (incl ICU)

✓ Inclusion

✔Cytoreductive surgery (removal of all visible peritoneal tumour)
✔HIPEC – heated intraperitoneal chemotherapy with standard drug and perfusion machine
✔Surgical oncologist's fee and team fees
✔General anaesthesia with epidural and anaesthetist's fee
✔Operation theatre charges, staplers and surgical consumables
✔ICU stay and private room – total 10–14 days hospitalisation
✔Nursing care, physiotherapy and dietitian support during the stay
✔Routine medicines, IV fluids, antibiotics and IV nutrition during the stay
✔Histopathology report of removed tissue
✔Routine blood tests and X-rays during the stay
✔Free: airport pick-up & drop, visa invitation letter, interpreter & coordinator (Satyug Healthcare)

✗ Exclusion

✖Pre-operative consultation, PET-CT, MRI, tumour markers and diagnostic laparoscopy
✖Extra ICU or hospital days beyond 14 days
✖Blood and blood products
✖High-cost or special chemotherapy drugs beyond the standard HIPEC drug
✖Systemic chemotherapy, targeted therapy or immunotherapy before or after surgery
✖Treatment of complications (re-operation, interventional drainage)
✖IHC and molecular tests on tumour
✖Medicines and stoma supplies after discharge
✖Hotel stay, food, local travel, airfare and visa fees

Know More About Procedure & Surgery

🇮🇳 ONCOLOGY PACKAGE — INDIA

Cytoreductive Surgery (CRS) + HIPEC in India

CRS + HIPEC removes all visible cancer from the abdomen and then washes it with heated chemotherapy, for selected patients with pseudomyxoma, peritoneal mesothelioma, and ovarian, colorectal, appendix or gastric cancer spread to the abdominal lining. It is performed by specialist teams at NABH and JCI accredited hospitals in India.

✅ Free Medical Opinion in 48–72 h🔥 Heated intra-abdominal chemotherapy💰 Starting USD 10,999✈️ Visa & Airport Support🗣️ Interpreter Available

⏱️

8–12 hrs

Surgery time

🏥

10–14 days

Hospital stay incl. ICU

📈

60–70%

10-yr survival, PMP*

📅

4–5 weeks

Total stay in India

📖 What is CRS + HIPEC?

The peritoneum is the thin, smooth lining that covers the inside of the abdomen and the organs within it. Some cancers – especially of the appendix, colon, ovary and stomach – can spread onto this lining as many small deposits. This is called peritoneal metastasis or peritoneal carcinomatosis. Rarer cancers such as pseudomyxoma peritonei (jelly-like tumour from the appendix) and peritoneal mesothelioma begin in the abdomen itself. Standard chemotherapy given into a vein reaches the peritoneum poorly.

Cytoreductive surgery (CRS) is a long operation in which the surgeon removes all visible tumour from the abdomen. This may include stripping the affected lining and removing parts of organs such as the bowel, spleen, gallbladder, omentum, uterus and ovaries. It is immediately followed by HIPEC (hyperthermic intraperitoneal chemotherapy): chemotherapy heated to about 41–43°C is circulated inside the abdomen for 30–90 minutes to kill microscopic cancer cells that cannot be seen. The heat makes the chemotherapy more effective, and very little reaches the rest of the body.

🖼️ Understand It in Pictures

💡 In simple words

Some cancers spread onto the lining of the belly. In one operation, the surgeon first removes all visible tumour (CRS), then fills the belly with heated chemotherapy (HIPEC) for a short time to kill tiny cancer cells left behind.

Cancer on the belly lining and CRS + HIPEC

CRS + HIPEC: normal vs abnormal explained in pictures

👀 Symptoms in Pictures

Symptoms that may need CRS + HIPEC - in pictures

🩻 Scans & Tests — What Doctors See

**CT scanner**
You lie still while the ring takes X-ray pictures in slices; a scan takes only a few minutes.
Image: Tomáš Vendiš, CC BY-SA 4.0, via Wikimedia Commons

**PET-CT scan picture**
Bright spots show areas where cancer cells are very active anywhere in the body.
Image: Eric Tse et al., CC BY 4.0, via Wikimedia Commons

🎬 The Treatment Journey in Pictures

📅 Recovery at a Glance

Drawings: Satyug Healthcare (simplified, not to scale). Photos: Wikimedia Commons; author and licence under each photo.

🩺 Conditions Treated

🟡

Pseudomyxoma peritonei (PMP)

Jelly-like tumour usually from the appendix; CRS + HIPEC is the standard treatment.

🎗️

Peritoneal mesothelioma

Rare cancer of the abdominal lining; CRS + HIPEC offers the best long-term survival.

🌸

Ovarian cancer

Stage III ovarian cancer at interval surgery after chemotherapy, and selected recurrences.

🔵

Colorectal and appendix cancer

Limited peritoneal spread without widespread liver or lung disease.

🟤

Gastric (stomach) cancer

Selected patients with limited spread, in specialist centres.

➕

Other selected tumours

Primary peritoneal cancer and some sarcomas, after tumour board review.

⚠️ Signs That May Need Evaluation

➤Increasing abdominal swelling or girth
➤Fluid in the abdomen (ascites)
➤Abdominal pain or heaviness
➤Early fullness and loss of appetite

➤Unexplained weight loss
➤Change in bowel habits or blockage symptoms
➤Raised tumour markers (CEA, CA-125, CA 19-9)
➤Peritoneal deposits seen on CT, PET-CT or during previous surgery

💡 CRS + HIPEC is only for carefully selected patients. It is not suitable when the cancer has spread widely to the liver, lungs or bones, when the peritoneal disease is too extensive to remove completely (very high PCI score), or when the patient is too weak for a long operation. These patients are treated with systemic chemotherapy, targeted therapy, PIPAC or supportive care.

🔬 Tests Before Treatment

Test	Why it is done
CT scan of chest, abdomen and pelvis with contrast	Maps the spread of disease and rules out distant spread.
PET-CT and / or MRI abdomen	Shows the extent of peritoneal disease more clearly.
Tumour markers (CEA, CA-125, CA 19-9)	Help with diagnosis and follow-up.
Biopsy and histopathology review	Confirms cancer type, which decides whether HIPEC will help.
Diagnostic laparoscopy (selected cases)	Measures the Peritoneal Cancer Index (PCI) before deciding.
Heart, lung, kidney and nutrition assessment	Confirms the patient can safely undergo a long surgery.
Colonoscopy / upper GI endoscopy	Checks the primary tumour in bowel or stomach cancers.

🏥 The Procedure — Step by Step

Tumour board decision

Surgical oncologist, medical oncologist and radiologist confirm that complete removal is possible.

Pre-surgery optimisation

Nutrition support, breathing exercises and bowel preparation.

Admission and anaesthesia

General anaesthesia with epidural for pain control.

Abdomen opened and PCI scored

The surgeon measures the spread of disease in 13 regions (PCI score).

Cytoreductive surgery

All visible tumour is removed, including affected lining and organs.

HIPEC

Heated chemotherapy (41–43°C) is circulated in the abdomen for 30–90 minutes.

Reconstruction

Bowel is joined again; a temporary stoma (bag) is sometimes needed.

Closure with drains

Drains and sometimes a feeding line are placed.

ICU care

Usually 2–3 days in ICU for monitoring of blood pressure, kidneys and blood counts.

Ward recovery and discharge

Gradual diet, walking and drain removal; discharge after 10–14 days in total.

⚖️ Types & Techniques

Technique	What is done	Best for
CRS + HIPEC (open, closed method)	Abdomen closed while heated chemo circulates	Most patients
CRS + HIPEC (open, coliseum method)	Abdomen kept open and chemo stirred by hand	Even distribution in complex cases
Interval CRS + HIPEC for ovarian cancer	After 3 cycles of chemotherapy, with cisplatin HIPEC	Stage III ovarian cancer (OVHIPEC-1 trial)
Laparoscopic CRS + HIPEC	Keyhole surgery for limited disease	Low-volume disease, selected PMP
PIPAC	Pressurised chemotherapy spray by laparoscopy	Patients not suitable for CRS + HIPEC

📊 In the OVHIPEC-1 randomised trial (NEJM 2018), adding HIPEC to interval surgery for stage III ovarian cancer improved median overall survival from about 34 to 46 months; in pseudomyxoma peritonei, complete CRS + HIPEC gives 10-year survival of about 60–70% in large series.

📅 Your Day-by-Day Plan in India

Day	What happens
Day 1	Arrival in India ✈️, airport pick-up and hotel check-in
Day 2–4	Surgical oncology consultation, CT / PET-CT review, fitness tests and tumour board
Day 5	Admission and CRS + HIPEC surgery
Day 5–8	ICU care (about 2–3 days)
Day 8–18	Ward recovery, diet and drain removal; discharge after 10–14 days in hospital
Day 19–30	Hotel recovery, wound and nutrition review; histopathology report
Day 30–35	Oncology review and plan for further chemotherapy – Fly home ✈️

🌱 Recovery After Treatment

🏥

Week 1

ICU then ward care; nutrition by drip or feeding tube; walking with support.

🥣

Week 2

Soft diet, drains removed, discharge after 10–14 days.

🚶

Weeks 3–4

Short walks, small frequent meals, wound checks; tiredness is normal.

💊

Weeks 4–8

Further chemotherapy may start, depending on cancer type.

🏢

2–3 months

Return to light work and normal daily activities.

📆

Long term

CT scan and tumour markers every 3–6 months for 2–3 years, then yearly.

🏆 Success Rate

Outcome	Result
10-year survival – pseudomyxoma peritonei after complete CRS + HIPEC	About 60–70%
5-year survival – peritoneal mesothelioma	About 45–50%
Median survival – stage III ovarian cancer with interval CRS + HIPEC (OVHIPEC-1)	About 46 months (vs 34 without HIPEC)
5-year survival – colorectal peritoneal spread after complete CRS	About 30–40%
Operative mortality at experienced centres	About 1–4%

*Results depend mainly on the cancer type, how much disease is present (PCI score), whether all visible tumour can be removed (complete cytoreduction), the patient's fitness and the experience of the team.

🩹 Risks & Possible Complications

CRS + HIPEC is a major operation. Serious complications occur in about 20–35% of patients at experienced centres. Possible risks include:

•Prolonged bowel slowdown (ileus) and nausea – common
•Leak from bowel joins or fistula – about 5–10%
•Infection or abscess in the abdomen or wound – about 10–15%
•Low blood counts from chemotherapy – about 5–10%
•Kidney strain from chemotherapy – about 2–5%, usually temporary
•Lung complications, pleural fluid or blood clots – about 5–10%
•Re-operation about 5–10%; death about 1–4%

💰 Cost of CRS + HIPEC in India

The cost of CRS + HIPEC in India starts from about USD 10,999. This includes the surgery, HIPEC chemotherapy and machine, anaesthesia, ICU care and a private room for 10–14 days. The cost varies with the extent of surgery, number of organs removed, ICU stay and complications.

Option / Hospital tier	Approx. cost (USD)	Hospital stay	Notes
CRS + HIPEC – this package	10,999	10–14 days, private room + ICU	Standard cytoreduction with HIPEC
CRS + HIPEC – extensive disease (high PCI)	13,000 – 16,000	14–21 days	Multiple organ resections, longer ICU
Pre-surgery work-up (PET-CT, markers, laparoscopy)	800 – 1,500	Outpatient / day care	If not done at home
PIPAC (per session)	3,000 – 4,000	2–3 days	For patients not suitable for CRS

⚠️ Final cost depends on the cancer type, PCI score, number of organs removed, chemotherapy drug used, ICU days and any complications. Quotes are confirmed after the specialist examines the patient in India.

CRS + HIPEC cost comparison India USA UK Turkey

📋 What the Package Includes

✅ Included

✔Cytoreductive surgery
✔HIPEC chemotherapy and perfusion machine
✔Surgeon and anaesthesia fees
✔ICU care
✔Private room, 10–14 days total
✔Routine medicines and consumables
✔Histopathology report
✔Free airport pick-up, visa letter and interpreter

❌ Not Included

✖PET-CT and pre-surgery tests
✖Diagnostic laparoscopy
✖Extra ICU or hospital days
✖Blood and blood products
✖Systemic chemotherapy before or after
✖Stoma supplies after discharge
✖Hotel stay after discharge
✖Flights and visa fees

✈️ Your Medical Travel Process with Satyug Healthcare

Medical travel journey to India for CRS + HIPEC

Step	Details
1. Send reports	Contrast CT scan of chest, abdomen and pelvis (images on CD or link), PET-CT or MRI if done, biopsy and histopathology report (with slides or blocks if available), previous operation notes, chemotherapy details, tumour markers (CEA, CA-125, CA 19-9) and a summary of current health.
2. Free opinion & quotes	Within 48-72 hours you receive opinions and cost estimates from 3-5 leading hospitals to compare.
3. Choose hospital & doctor	We help you compare doctors, success rates, room options and total budget.
4. Medical visa	The hospital issues a Visa Invitation Letter (VIL) to the Indian Embassy. The patient and up to 2 attendants apply for an e-Medical / Medical Attendant visa.
5. Travel planning	Flight guidance, wheelchair assistance, airport pick-up, hotel or guest house near the hospital.
6. Treatment in India	Your coordinator and interpreter stay with you for admission, treatment, discharge and billing.
7. Return & follow-up	Fit-to-fly letter, medicines, and online follow-up with your doctor after you return home.

🎒 Travel Checklist

📌Valid passport (6+ months) for the patient and attendants, plus 10 passport-size photos each
📌Medical visa / e-visa and the hospital’s Visa Invitation Letter
📌All CT / PET-CT scans on CD / link, biopsy reports, operation notes, chemotherapy records and prescriptions
📌Yellow fever vaccination certificate (mandatory for travellers from African countries)
📌Polio vaccination certificate where applicable
📌Declare cash above USD 5,000 at the airport; hospitals accept wire transfer and cards
📌Foreigners staying longer than permitted must register with the FRRO — our team assists

⭐ Why Choose Satyug Healthcare?

🏥

Top Accredited Hospitals

Leading peritoneal surface malignancy centres such as Max Super Speciality Hospital Saket, Medanta – The Medicity, Fortis Memorial Research Institute Gurugram, Rajiv Gandhi Cancer Institute, BLK-Max, Artemis and Apollo hospitals.

👨‍⚕️

Senior Specialists

Surgery is performed by surgical oncologists with dedicated training and experience in peritoneal surface malignancies and HIPEC.

💵

Transparent Pricing

Multiple written quotes to compare — no hidden charges, no extra fee for our service.

🤝

End-to-End Support

Visa, airport pick-up, accommodation, interpreter and 24/7 coordinator.

❓ Frequently Asked Questions

➤ What is the cost of CRS + HIPEC in India?

It starts from about USD 10,999, including surgery, HIPEC, ICU care and 10–14 days in a private room. Extensive surgery costs more.

➤ How long does the surgery take?

Usually 8–12 hours, depending on how much disease needs to be removed.

➤ How long will I stay in hospital and in India?

About 10–14 days in hospital including ICU. Plan to stay in India for about 4–5 weeks.

➤ Am I a candidate for CRS + HIPEC?

It depends on the cancer type, the amount of disease (PCI score), whether all tumour can be removed and your fitness. Send your CT / PET-CT and biopsy reports for a free assessment.

➤ Which cancers does HIPEC work best for?

Pseudomyxoma peritonei and peritoneal mesothelioma, followed by ovarian cancer and selected colorectal and appendix cancers. Benefit in stomach cancer is more limited.

➤ What is the success rate?

In pseudomyxoma, about 60–70% of patients are alive at 10 years after complete surgery. In ovarian cancer, HIPEC added about one year of survival in a major trial. Results depend on cancer type and complete removal.

➤ Is it painful?

Pain is controlled with an epidural and medicines. Most patients are walking within a few days.

➤ Will I need a stoma (bag)?

Sometimes a temporary stoma is needed to protect bowel joins. It can usually be closed after a few months.

➤ What are the main risks?

Bowel slowdown, infection, leaks, low blood counts and kidney strain. Serious complications occur in about 20–35%, and death in about 1–4% at experienced centres.

➤ Will I need chemotherapy after surgery?

Often, depending on the cancer type. Your oncologist will advise; it can be given in India or at home.

➤ When can I return to work?

Most patients return to light work in 2–3 months.

💬 Get a Free Opinion & Cost Estimate

Send your medical reports today and receive opinions from India’s top specialists within 48-72 hours.

📞 +91-8860606766 | +91-9910655125 | ✉️ query@satyughealthcare.com

Medical disclaimer: This page is for general information and does not replace a consultation with a qualified specialist. Treatment plans and costs are confirmed only after the patient is examined. Sources: PSOGI / Peritoneal Surface Oncology Group International consensus statements; van Driel WJ et al., OVHIPEC-1 trial, NEJM 2018; Quénet F et al., PRODIGE 7 trial, Lancet Oncology 2021; Chua TC et al., pseudomyxoma peritonei outcomes, J Clin Oncol 2012; NCCN Guidelines (ovarian, colon cancer) 2024; NCBI StatPearls: Hyperthermic Intraperitoneal Chemotherapy. Infographics: Satyug Healthcare.