Neuromuscular junction transmission defect Treatment in India

ABOUT BLOG

What is Neuromuscular Junction Defect?

Neuromuscular junction transmission defect is a problem with communication from the nerve to the muscle. Generally, acetylcholine is released from the end of the nerve and attaches to the muscle causing contraction of the muscle. A defect in neuromuscular transmission can occur when there is a deficit in the amount of acetylcholine released from the nerve or acetylcholine attachment to the muscle is blocked.

Symptoms

• Muscular weakness
• Muscle wastage
• Muscular cramps
• Muscle spasticity (stiffness), which later causes joint or skeletal deformities
• Muscle pain
• Breathing difficulties
• Swallowing difficulties

Causes

• Genetic mutation
• Viral infection
• Autoimmune disorder
• Hormonal disorder
• Metabolic disorder
• Dietary deficiency
• Certain drugs and poisons
• Unknown factors.

Diagnosis

• Electrical tests known as nerve conduction studies (to measure the ability of nerves to conduct electricity)
• Electromyography (EMG) to examine the health of a muscle
• Blood tests
• Muscle biopsies
• Genetic testing.

Treatment

Treatment varies widely, according to the individual disorder, and some conditions are more easily treated than others. Some treatment options include medical therapy, including immunosuppressive drugs, pain management and assistive devices. Doctor can also offer apheresis, which filters out antibodies in the blood associated with neuromuscular disease that causes weakness and other problems. This can allow us to get ahead of some diseases and treat them more effectively.

If you have any related query, you can send us your report on below mention email address or you can call us or whatsApp for any second opinion.

Video/tele consultation also available

E-mail address- query@satyughealthcare.com
Phone number- +91888-242-4372, +91991-065-5125

Frequently asked questions

Q. Which disease affects neuromuscular junction?

Autoimmune diseases occur when the body's immune system begins to target its own cells, often causing harmful effects. The neuromuscular junction diseases present within this subset are myasthenia gravis, and Lambert-Eaton syndrome.

Q. Is neuromuscular disease curable?

There is no cure for most neuromuscular disorders, but some can be effectively managed and treated. Some common interventions include: Drug therapy – Immunosuppressive drugs can treat certain muscle and nerve diseases and diseases of the nerve-muscle junctions.

Q. What is a severe neuromuscular disease?

Neuromuscular diseases affect the function of muscles due to problems with the nerves and muscles in your body. The most common symptom of these diseases is muscle weakness.

Q. What are the 3 parts of a neuromuscular junction?

The structure of NMJ can be divided into three main parts: a presynaptic part (nerve terminal), the postsynaptic part (motor endplate), and an area between the nerve terminal and motor endplate (synaptic cleft).