Allogeneic Bone Marrow Transplant Package
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Written & reviewed by Vikram Kashyap, Medical Consultant, Satyug Healthcare
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| Surgery Name | Cost | Room | Hospitalization |
|---|---|---|---|
| Allogeneic Bone Marrow Transplant Package | 21500 USD | Single | stay of the patient in the hospital for up to 30 days |
✓ Inclusion
- ✔Haematologist and BMT physician consultations
- ✔Pre-transplant work-up: blood tests, echo, ECG, lung function, CT chest and infection screening
- ✔Donor medical evaluation and sibling stem cell collection (growth-factor injections and apheresis)
- ✔Central venous line (Hickman / PICC) insertion
- ✔Conditioning chemotherapy as per protocol
- ✔Stem cell infusion (Day 0)
- ✔Hospital stay of up to 30 days in a single HEPA-filtered BMT room
- ✔Routine antibiotics, GVHD-prevention drugs and supportive medicines as per package
- ✔Standard blood and platelet transfusions as per package
- ✔Nursing care, diet and daily doctor rounds
- ✔Discharge summary and follow-up plan
- ✔Free: airport pick-up & drop, visa invitation letter, interpreter & coordinator (Satyug Healthcare)
✗ Exclusion
- ✖HLA typing of patient and family members
- ✖Unrelated donor search, registry and courier charges
- ✖Haploidentical or unrelated donor transplant upgrades
- ✖High-cost antifungal, antiviral (e.g. CMV) and biologic drugs beyond package
- ✖Extended ICU stay, ventilator support or dialysis
- ✖Hospital stay beyond 30 days
- ✖Outpatient visits, tests and medicines after discharge until day 100
- ✖Accommodation and food outside hospital for patient, donor and attendants
- ✖Air tickets, visa fees and travel insurance
- ✖Treatment of unrelated medical conditions
Know More About Procedure & Surgery
🇮🇳 BMT PACKAGE — INDIA
Allogeneic Bone Marrow Transplant in India
Donor stem cell transplant for leukaemia, thalassaemia, aplastic anaemia and other blood disorders, done by experienced haemato-oncology and BMT teams at accredited Indian hospitals – often at one-quarter to one-fifth of US or European prices.
✅ Free Medical Opinion in 48–72 h🩸 Matched & Half-Matched Donors💰 Starting USD 21,500✈️ Visa & Airport Support🗣️ Interpreter Available
🧬
2–3 weeks
Engraftment time
🏥
≤ 30 days
Hospital stay in BMT unit
📈
70–90%
Survival in benign diseases*
📅
~3 months
Total stay in India
📖 What is an Allogeneic Bone Marrow Transplant?
Bone marrow is the soft, spongy tissue inside large bones. It contains stem cells – young cells that grow into red blood cells (carry oxygen), white blood cells (fight infection) and platelets (stop bleeding). In diseases such as leukaemia, thalassaemia or aplastic anaemia, the marrow is cancerous, faulty or empty, so the body cannot make healthy blood.
In an allogeneic transplant ("allo" means "other"), healthy stem cells are taken from a donor – usually a brother or sister, a matched unrelated volunteer, or a half-matched (haploidentical) parent or child. First the patient receives strong chemotherapy, sometimes with radiation (called conditioning), to clear the diseased marrow. The donor cells are then given through a drip, like a blood transfusion. They travel to the bones and start making new, healthy blood. The donor immune system can also attack leftover cancer cells – the "graft-versus-leukaemia" effect. It is also called an allogeneic stem cell transplant (allo-SCT or allo-HSCT).
🖼️ Understand It in Pictures
💡 In simple words
Some blood cancers and bone marrow diseases stop the marrow making healthy blood cells. In an allogeneic transplant, strong treatment clears the sick marrow and stem cells from a matched donor are given through a drip. They settle in the bones and grow a new blood and immune system.
Healthy vs diseased blood, and after transplant
👀 Symptoms in Pictures
🩻 Scans & Tests — What Doctors See
🎬 The Treatment Journey in Pictures
📅 Recovery at a Glance
Drawings: Satyug Healthcare (simplified, not to scale). Photos: Wikimedia Commons; author and licence under each photo.
🩺 Conditions Treated
🎗️
Acute leukaemia (AML / ALL)
High-risk or relapsed acute leukaemia, usually transplanted once in remission.
🩸
Thalassaemia major
A cure for transfusion-dependent thalassaemia, best done in childhood before iron overload damages organs.
🦴
Aplastic anaemia
Severe marrow failure; a matched sibling transplant is first-line treatment for younger patients.
🧬
Myelodysplastic syndrome (MDS) & myelofibrosis
Higher-risk marrow cancers where transplant is the only cure.
🔴
Sickle cell disease
Severe disease with strokes, frequent pain crises or chest syndrome.
👶
Immune deficiencies & rare disorders
Conditions such as SCID, Fanconi anaemia and some metabolic diseases in children.
⚠️ Signs That a Transplant May Be Needed
- ➤Leukaemia that has relapsed or is high-risk
- ➤Need for regular blood transfusions
- ➤Very low blood counts on repeated tests
- ➤Frequent or serious infections
- ➤Easy bruising or bleeding
- ➤Severe tiredness and paleness (anaemia)
- ➤Growing spleen or liver from blood disease
- ➤Doctor advice that chemotherapy alone will not cure
💡 A donor transplant is not the first step for everyone. Many leukaemias and lymphomas are cured with chemotherapy alone, some myeloma and lymphoma patients need only an autologous (own-cell) transplant, and some older patients with aplastic anaemia do well with immunosuppressive drugs. Your haematologist decides based on disease type, risk group, age and donor availability.
🔬 Tests Before Treatment
| Test | Why it is done |
|---|---|
| HLA typing (patient and donors) | Checks how well the donor's tissue type matches the patient – the most important test for choosing a donor. |
| Bone marrow biopsy & MRD test | Confirms the disease status and that leukaemia is in remission before transplant. |
| Complete blood count, kidney & liver tests | Make sure the body can safely handle conditioning chemotherapy. |
| Echocardiogram & ECG | Checks the heart pumping before strong chemotherapy. |
| Lung function test & CT chest | Looks for lung problems or hidden infection. |
| Infection screening (HIV, hepatitis B/C, CMV, TB) | Infections are treated or watched closely during low immunity. |
| Donor-specific antibody test & donor health check | Ensures the graft will not be rejected and the donor is fit to donate. |
🏥 The Procedure — Step by Step
1
Arrival and assessment
The BMT team reviews reports, repeats key tests and confirms the donor match.
2
Donor work-up
The donor has a medical check, blood tests and counselling; the hospital checks the donor's identity and relationship documents.
3
Central line insertion
A soft tube (Hickman or PICC line) is placed in a large vein for chemotherapy, blood and nutrition.
4
Admission to BMT unit
The patient moves into a single HEPA-filtered isolation room to reduce infection.
5
Conditioning
5–10 days of high-dose chemotherapy, sometimes with radiation, clears the diseased marrow.
6
Stem cell collection
The donor receives growth-factor injections and cells are collected from the blood (apheresis) or marrow.
7
Day 0 – stem cell infusion
Donor cells are given through the central line over 1–2 hours, like a blood transfusion.
8
Low-count phase
For about 2–3 weeks counts are very low; antibiotics, transfusions and GVHD-prevention drugs are given.
9
Engraftment
New white cells and platelets appear, usually in 2–3 weeks, showing the graft is working.
10
Discharge and close follow-up
The patient leaves hospital and is seen 1–2 times a week as an outpatient until about day 90–100.
⚖️ Types of Allogeneic Transplant
| Donor type | What is done | Best for |
|---|---|---|
| Matched sibling donor (MSD) | Brother or sister with a full 10/10 HLA match donates cells | Best results; first choice when available |
| Matched unrelated donor (MUD) | Cells from a volunteer found in Indian or international registries | Patients without a matched sibling; extra registry and courier cost |
| Haploidentical (half-matched) | Parent, child or sibling with a 50% match; uses post-transplant cyclophosphamide | When no full match exists; donor almost always available |
| Reduced-intensity conditioning (RIC) | Gentler chemotherapy relying more on donor immune effect | Older or less fit patients |
| Myeloablative conditioning (MAC) | Full-strength chemotherapy ± total body irradiation | Younger, fit patients with leukaemia or thalassaemia |
📊 In large international registry data (CIBMTR/EBMT), matched-sibling transplants for thalassaemia in children have overall survival around 90% and thalassaemia-free survival about 80–90%, while haploidentical transplants with post-transplant cyclophosphamide now give results close to matched unrelated donors in leukaemia.
📅 Your Day-by-Day Plan in India
| Day | What happens |
|---|---|
| Day 1 | Arrival in India, airport pick-up and hotel or guest-house check-in ✈️ |
| Day 2–7 | Haematologist consultation, pre-transplant tests, donor HLA confirmation and work-up |
| Day 8–10 | Central line placement and admission to the BMT unit |
| Day 10–18 | Conditioning chemotherapy; donor stem cell collection |
| Day 18 (Day 0) | Stem cell infusion |
| Next 2–3 weeks | Low-count phase and engraftment in the BMT room (hospital stay up to 30 days) |
| Day 40–100 | Outpatient visits 1–2 times a week near the hospital; blood tests, drug levels, GVHD and CMV monitoring |
| Around Day 100 | Final review, bone marrow / chimerism test and travel clearance – Fly home ✈️ |
🌱 Recovery After Treatment
🏥
Weeks 1–4
In the isolation room; mouth ulcers, tiredness and low appetite are common and are treated.
🌱
Weeks 3–5
Counts recover; discharge to a nearby clean apartment with strict hygiene.
💊
Months 1–3
Daily immunosuppressive and preventive medicines; frequent blood tests for drug levels and infections.
😷
Months 3–6
Back home; masks in crowds, safe food, avoid sick contacts. Local doctor coordinates with the Indian team.
💉
Months 6–12
Immunosuppression is slowly reduced; childhood vaccines are repeated from about 6–12 months.
🏃
After 1 year
Most survivors return to school, work and normal life, with yearly check-ups for long-term effects.
🏆 Success Rate
| Outcome | Result |
|---|---|
| Thalassaemia, matched sibling (children) | About 85–90% survival, 80–90% cured |
| Severe aplastic anaemia, matched sibling | About 75–90% long-term survival |
| AML in first remission | About 50–65% long-term survival |
| Haploidentical transplant (leukaemia) | Results close to matched unrelated donors in recent studies |
| Engraftment | Over 90% of patients engraft within 2–4 weeks |
Results depend most on the disease and its stage, the patient's age and fitness, how well the donor matches, and how many infections or transfusions the patient had before transplant. Transplanting early, in remission, gives the best chance.
🩹 Risks & Possible Complications
An allogeneic transplant is a major treatment, and the team watches closely for these problems:
- •Infections (bacterial, fungal, viral such as CMV) – very common during low counts
- •Mouth ulcers, nausea, diarrhoea and hair loss from conditioning
- •Acute graft-versus-host disease (GVHD) – about 30–50%, usually mild to moderate
- •Chronic GVHD – about 30–50% of survivors, affecting skin, eyes, mouth, liver or lungs
- •Graft failure or rejection – about 2–10%, higher in thalassaemia and haplo transplants
- •Liver veno-occlusive disease (SOS) and organ toxicity – less common
- •Infertility, cataract, thyroid problems and second cancers in the long term
💰 Cost of Allogeneic BMT in India
The cost of an allogeneic bone marrow transplant in India starts from about USD 21,500 for a matched sibling donor transplant with a single room. It usually covers the pre-transplant work-up, conditioning chemotherapy, stem cell collection from the donor, the BMT room stay of up to 30 days and routine medicines. Unrelated donor searches, haploidentical transplants, long ICU stays or costly antifungal and antiviral drugs add to the cost.
| Option / Hospital tier | Approx. cost (USD) | Hospital stay | Notes |
|---|---|---|---|
| Matched sibling allogeneic BMT (this package) | From 21,500 | Up to 30 days, single room | Standard package; donor is brother or sister |
| Haploidentical (half-matched) BMT | 25,000 – 35,000 | 4–5 weeks, single room | Parent, child or sibling donor; more drugs and monitoring |
| Matched unrelated donor (MUD) BMT | 35,000 – 50,000+ | 4–5 weeks, single room | Includes registry search and international cell courier |
| Premium hospital / complex cases | 30,000 – 60,000 | Variable | Relapsed disease, severe GVHD or long ICU care |
⚠️ Final cost depends on the disease, donor type, conditioning plan, infections, blood product needs and length of stay. Outpatient care and accommodation until about day 100 are extra. Quotes are confirmed after the haematologist examines the patient in India.
📋 What the Package Includes
✅ Included
- ✔Pre-transplant work-up tests
- ✔Conditioning chemotherapy
- ✔Donor stem cell collection (sibling)
- ✔Single HEPA-filtered room, up to 30 days
- ✔BMT specialist and nursing care
- ✔Routine medicines and consumables
- ✔Airport pick-up, visa letter, interpreter
❌ Not Included
- ✖HLA typing of extra family members
- ✖Unrelated donor registry search & courier
- ✖Expensive antifungal / antiviral drugs beyond package
- ✖Extended ICU stay or ventilator
- ✖Outpatient care after discharge
- ✖Accommodation and food outside hospital
- ✖Air tickets and visa fees
✈️ Your Medical Travel Process with Satyug Healthcare
| Step | Details |
|---|---|
| 1. Send reports | Latest complete blood count, bone marrow biopsy and flow cytometry report, cytogenetics / molecular reports (for leukaemia), HLA typing of the patient and siblings if done, treatment summary with chemotherapy cycles, transfusion history, and ferritin level for thalassaemia. |
| 2. Free opinion & quotes | Within 48-72 hours you receive opinions and cost estimates from 3-5 leading hospitals to compare. |
| 3. Choose hospital & doctor | We help you compare doctors, success rates, room options and total budget. |
| 4. Medical visa | The hospital issues a Visa Invitation Letter (VIL) to the Indian Embassy. The patient and up to 2 attendants apply for an e-Medical / Medical Attendant visa. |
| 5. Travel planning | Flight guidance, wheelchair assistance, airport pick-up, hotel or guest house near the hospital. |
| 6. Treatment in India | Your coordinator and interpreter stay with you for admission, treatment, discharge and billing. |
| 7. Return & follow-up | Fit-to-fly letter, medicines, and online follow-up with your doctor after you return home. |
🎒 Travel Checklist
- 📌Valid passport (6+ months) for the patient and attendants, plus 10 passport-size photos each
- 📌Medical visa / e-visa and the hospital’s Visa Invitation Letter
- 📌All blood reports, bone marrow and genetic reports, HLA typing results, treatment summary and prescriptions
- 📌Yellow fever vaccination certificate (mandatory for travellers from African countries)
- 📌Polio vaccination certificate where applicable
- 📌Declare cash above USD 5,000 at the airport; hospitals accept wire transfer and cards
- 📌Foreigners staying longer than permitted must register with the FRRO — our team assists
⭐ Why Choose Satyug Healthcare?
🏥
Top Accredited Hospitals
Leading BMT centres such as Artemis Gurugram, Fortis Memorial Gurugram, BLK-Max Delhi, Max Saket, Medanta Gurugram, Apollo Chennai, Narayana Health City Bengaluru and Manipal Hospitals, with JCI or NABH accreditation and dedicated HEPA-filtered BMT units.
👨⚕️
Senior Specialists
Transplants are led by haemato-oncologists and BMT physicians with experience of hundreds of matched, unrelated and haploidentical transplants in adults and children.
💵
Transparent Pricing
Multiple written quotes to compare — no hidden charges, no extra fee for our service.
🤝
End-to-End Support
Visa, airport pick-up, accommodation, interpreter and 24/7 coordinator.
❓ Frequently Asked Questions
➤ How much does an allogeneic bone marrow transplant cost in India?
A matched sibling transplant starts from about USD 21,500. Haploidentical transplants usually cost USD 25,000–35,000 and matched unrelated donor transplants USD 35,000–50,000 or more. Outpatient care and stay until day 100 are extra.
➤ Who can be my donor?
The best donor is a brother or sister with a full HLA match – each sibling has about a 25% chance of matching. If none matches, a half-matched parent, child or sibling (haploidentical) or a matched volunteer from a registry can donate.
➤ Does the donor have to travel to India?
Yes, a family donor must come to India for tests and stem cell collection. Hospitals ask for HLA typing reports of all brothers and sisters (to find the best match), blood group reports of the patient and donor, and identity and relationship documents as per hospital policy.
➤ How long will I stay in hospital?
This package includes up to 30 days in the BMT unit. Most patients engraft and go home from hospital in about 3–5 weeks after admission.
➤ How long must I stay in India?
Plan for about 3 months in total. After discharge you stay close to the hospital until around day 90–100 because infections and GVHD are most common in this period.
➤ What is the success rate?
It depends on the disease. Children with thalassaemia and a matched sibling have about 85–90% survival, and severe aplastic anaemia about 75–90%. For leukaemia, long-term survival is about 50–65% when transplanted in first remission.
➤ Is the procedure painful?
The stem cell infusion itself is painless, like a blood transfusion. Mouth ulcers and stomach upset from chemotherapy can be painful, and these are treated with strong pain relief and good nursing.
💬 Get a Free Opinion & Cost Estimate
Send your medical reports today and receive opinions from India’s top specialists within 48-72 hours.
📞 +91-8860606766 | +91-9910655125 | ✉️ query@satyughealthcare.com
Medical disclaimer: This page is for general information and does not replace a consultation with a qualified specialist. Treatment plans and costs are confirmed only after the patient is examined. Sources: NCBI StatPearls: Allogeneic Hematopoietic Stem Cell Transplantation; NHS: Stem cell and bone marrow transplants; Mayo Clinic: Bone marrow transplant; Cleveland Clinic: Bone marrow transplant; CIBMTR & EBMT registry reports; ASTCT / EBMT indication guidelines 2022. Infographics: Satyug Healthcare.
Frequently Asked Questions
A procedure in which a patient receives healthy stem cells (blood-forming cells) to replace their own stem cells that have been destroyed by treatment with radiation or high doses of chemotherapy.
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Allogeneic bone marrow transplant in India from USD 21,500 – sibling, unrelated & haplo donors at JCI/NABH BMT units, 30-day stay, free opinion & visa help.
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